PTGDS Polyclonal Antibody for Human(Homo sapiens) | EIAab.comPTGDS Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > PTGDS(Gene name) > Human

PTGDS (Gene name),

Prostaglandin-H2 D-isomerase (Protein name ), PTGDS_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

PTGDS(PDS);

Protein name:

Prostaglandin-H2 D-isomerase;

Alternative:

Cerebrin-28;Beta-trace protein;Lipocalin-type prostaglandin-D synthase;Glutathione-independent PGD synthase;Prostaglandin-D2 synthase(PGD2 synthase;PGDS;PGDS2);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer.

Function:

Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Subcellular Location:

Rough endoplasmic reticulum Nucleus membrane Golgi apparatus Cytoplasm perinuclear region Secreted Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.

Protein Attributes:

Sequence length:

190

Sequence:

50:

100:

150:

190:

RTQTPRAELK | EKFTAFCKAQ | GFTEDTIVFL | PQTDKCMTEQ |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00061

SMR:

P41222

UniGene:

Hs.446429

KEGG:

hsa:5730

MIM:

176803

STRING:

9606.ENSP00000360687

String:

P41222

Uniprot:

P41222

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ELISA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

E0167h

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96T

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ELISA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

E0167r

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96T

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ELISA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

E0167d

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96T

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ELISA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

E0167m

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MSDS:

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Packing:

96T

ELISA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

E0167b

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MSDS:

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96T

ELISA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

E0167p

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MSDS:

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96T

CLIA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

U0167d

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MSDS:

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Packing:

96T

CLIA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

U0167m

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MSDS:

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Packing:

96T

CLIA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

U0167h

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

U0167p

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

U0167b

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MSDS:

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Packing:

96T

CLIA Kit for Human Prostaglandin-H2 D-isomerase

Cat.:

U0167r

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Human Prostaglandin-H2 D-isomerase

Cat.:

P0167Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Prostaglandin-H2 D-isomerase

Cat.:

P0167Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Prostaglandin-H2 D-isomerase

Cat.:

P0167Rb-m

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Monoclonal Antibody for Human Prostaglandin-H2 D-isomerase

Protein for Human Prostaglandin-H2 D-isomerase